HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 20473962, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | N-(Aminocarbonyl)-2-thiophenecarboxamide | HCID 395032 | — |
| Reactant | 4-Amino-1-(2-naphthyl)methylpiperidine | HCID 11195823 | — |
| Product | HCID 20473962 | HCID 20473962 | — |
Reaction Steps
4-Amino-1-(naphth-2-ylmethyl)piperidine (1.0 g, 0.0047 m) and 1-(then-2-oyl)urea (0.65 g, 0.0042 m) in pyridine (5 cm3) was refluxed for 9.5 hours. The solvent was evaporated, water added, and the precipitated title compound filtered and washed well with water. This was recrystallised from ethanol, converted to the hydrochloride salt in ethanol with ethanolic HCl, and recrystallised from ethanol, 0.5 g, at the hydrochloride, m.p. 217°-219° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04426387 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-860ac4c7001642e8b49ae5721479d9c7 |
| Source note | uspto-grants-1984_01 |