Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 1-Benzoyl-1-methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | 1-Methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea | HCID 19762408 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-Benzoyl-1-methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea | HCID 12942344 | — |
반응 단계
1-Methyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea (1.4 g.) (prepared by reacting 4-amino-1-(naphth-2-ylmethyl)piperidine with methyl isocyanate) in toluene (30 cm3) was acylated using benzoyl chloride (0.92 g) in presence of pyridine (0.6 g) to give the title compound: m.p. of HCl, hemihydrate salt=164°-166° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04426387 |
| 출처 데이터셋 | uspto-grants-1984_01 |
| ORD ID | ord-1262fa90d49a4ae2af7f1556b77f74dc |
| 출처 메모 | uspto-grants-1984_01 |