HCID 18456948, compound → HCID 17856278, compound

HRID 229579Notes

Reaction equation

C(OC([NH:8][CH2:9][CH2:10][C:11]1[CH:23]=[CH:22][C:21]([CH:24]([CH3:26])[CH3:25])=[CH:20][C:12]=1[O:13][CH2:14][CH2:15][CH2:16][C:17]([O-:19])=[O:18])=O)(C)(C)C.[CH2:27](O)[CH3:28].[ClH:30]>>[ClH:30].[NH2:8][CH2:9][CH2:10][C:11]1[CH:23]=[CH:22][C:21]([CH:24]([CH3:25])[CH3:26])=[CH:20][C:12]=1[O:13][CH2:14][CH2:15][CH2:16][C:17]([O:19][CH2:27][CH3:28])=[O:18]

Participants

Reactant 2

HCID 18456948HCID 18456948, compound

HCID 21887872Ethanol hydrochloride

Product 1

HCID 17856278HCID 17856278, compound

Procedure

4-[2-(2-tert-Butoxycarbonylaminoethyl)-5-isopropylphenoxy]-butyrate (0.283 g) was dissolved in 10 mL of 35% hydrogen chloride ethanol solution, and the mixture was stirred at room temperature for 5 hours. The solvent was removed under reduced pressure to give 0.235 g of ethyl 4-[2-(2-aminoethyl)-5-isopropylphenoxy]butyrate hydrochloride.

Workup

customThe solvent was removed under reduced pressure

Sources & evidence

ORD record: ord-85b949d2fa6b4c01b67012b5e6a9b53d
Source dataset: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07563822B2

Reaction notes

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