Acetic Anhydride → HCID 20474114, compound

Participants

Reaction Steps

Into a 100 ml round bottomed flask equipped with an efficient condenser and a calcium chloride tube were placed 10 ml of acetic anhydride and 0.5 g of 2-(4'-chlorobenzyl)-hexahydro-1,2,4-triazine-3,5 dione. The mixture was refluxed for 3 hours, then was cooled and poured on ice water, and left overnight. The crystals that separated were filtered off by suction and dried. The product was recrystallized from isopropanol to give 0.3 g (60%) of 1-acetyl-2-(4'-chlorobenzyl)-hexahydro-1,2,4-triazine-3,5-dione; m.p. 100°.

Provenance & Evidence