Methyl isothiocyanate → N-[4-(3-methoxy-2-pyridyl)butyl]-N'-methylthiourea

HRID 2295890Notes

Reaction equation

HRID 2295890 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[C:11]([O:12][CH3:13])=[CH:10][CH:9]=[CH:8][N:7]=1.[CH3:14][N:15]=[C:16]=[S:17]>>[CH3:13][O:12][C:11]1[C:6]([CH2:5][CH2:4][CH2:3][CH2:2][NH:1][C:16]([NH:15][CH3:14])=[S:17])=[N:7][CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 11167Methyl isothiocyanateHCID 130600284-(3-Methoxypyridin-2-yl)butan-1-amine

Product 1

HCID 20474234N-[4-(3-methoxy-2-pyridyl)butyl]-N'-methylthiourea

Procedure

Reaction of 2-(4-aminobutyl)-3-methoxypyridine with methyl isothiocyanate gives N-[4-(3-methoxy-2-pyridyl)butyl]-N'-methylthiourea.

Sources & evidence

ORD record
ord-ab677597f31b41fc8320d85e13fecfbe
Source dataset
uspto-grants-1984_01
Patent number
US04426526

Reaction notes

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