1-Butanol → HCID 53831434, compound

Participants

Reaction Steps

To 10.9 g. of potassium hydroxide of the same grade used in the examples above was added 50 ml. of butanol, and the mixture was stirred for 1 hour. To it was added 5.0 g. of 1,1,1-trichloro-2-(3-chloro-2-methylphenyl)ethane, and the mixture was stirred under reflux at 115° for 6 hours and allowed to cool overnight to ambient temperature. The mixture was then worked up as described in Example 4 above to obtain 4.5 g. of crude product as the major product. It was then taken up in 15 ml. of butanol and stirred with 40 ml. of 1 N hydrochloric acid at ambient temperature for 30 minutes. The layers were then separated, extracted and dried as described in Example 5 above to obtain 3.41 g. of product, found to be 92% pure by vapor phase chromatography.

Provenance & Evidence