Methane → HCID 23009692, compound

Participants

Reaction Steps

19.1 g (0.1 mol) of 2,6-diamino-3,4-dichlorotoluene are hydrogenated with hydrogen under a total pressure of 180 bar in an autoclave, in the presence of 500 ml of methanol, 15.4 g (0.2 mol) of ammonium acetate and 2 g of 1% strength platinum on medicinal charcoal, at 150° C. After separating off the catalyst by filtration and removing the solvent, the residue if taken up in water and the mixture is rendered neutral with sodium hydroxide solution and extracted with methylene chloride. 2,6-Diamino-4-chlorotoluene is obtained in a yield of 97.1% of theory; the purity is 95.3%.

Provenance & Evidence