Methanesulfonyl chloride → HCID 10878028, compound

Participants

Reaction Steps

232 g (2 moles) of 3,3-dimethyl-4-hydroxy-2-butanone (for the preparation, see Beilstein H 1 E III 3239, IV 4030 and Bull. Soc. Chim.France 1964, 2849) were reacted with 229 g (2 moles) of methanesulphonyl chloride in 700 ml of absolute pyridine at 0° to 5° C. After leaving the mixture to stand at 20° C. for 12 hours, it was diluted with methylene chloride and extracted by shaking with ice-water. The organic phase was dried, and freed from the solvent in vacuo, and the residue was fractionated over a column. 332 g (that is to say 86% of theory) of 2,2-dimethyl-3-oxo-butyl methanesulphonate were isolated at a boiling point0.12 of 106° to 120° C. ##STR12##

Provenance & Evidence