HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → butyl (tetrahydro-2H-pyran-2-yloxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| Reactant | Butyl Glycolate | HCID 81882 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Product | butyl (tetrahydro-2H-pyran-2-yloxy)acetate | HCID 54188463 | — |
Reaction Steps
84 g of 3,4-dihydro-2H-pyran and 132 g of glycolic acid butyl ester are dissolved at room temperature. To this solution are added 0.5 ml of concentrated hydrochloric acid, whereupon the temperature immediately rises to 90°. The solution is cooled to room temperature and stirred for 2 hours. After the addition of 1 g of sodium bicarbonate, the crude product is distilled under 17 Torr to obtain 2-(tetrahydropyran-2-yloxy)-acetic acid butyl ester, B.P. 127°/17 Torr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04427590 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-f6b175dcce014e3f9dabc4ceb9a87aaa |
| Source note | uspto-grants-1984_01 |