HuagongsheHuagongshe Chemistry Print Report · For research reference only
Erythromycin → 12-Deoxyerythronolide A
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Erythromycin | HCID 12560 | — |
| Reactant | oleandomycin | HCID 72493 | — |
| Product | 12-Deoxyerythronolide A | HCID 441113 | — |
Reaction Steps
Under HPLC the peak corresponding to P 15153 has a retention time with respect to erythromycin A of 0.64 and with respect to oleandomycin of 0.99. For the above four antibiotics, which are obtained in admixture from erythronolide B, after 100 hours of fermentation and before the isolation, the total antibiotic activity, expressed as activity of erythromycin A, is about 120-150 mcg/ml.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04429115 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-e4cb5bea6e7b4cf281cb8e5038b42872 |
| Source note | uspto-grants-1984_01 |