HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 3-Amino-1-phenyl-5-(2-pyridyl)-1,2-dihydropyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 3-Nitro-1-phenyl-5-(2-pyridyl)-1,2-dihydropyridin-2-one | HCID 22318956 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | 3-Amino-1-phenyl-5-(2-pyridyl)-1,2-dihydropyridin-2-one | HCID 22319119 | 83.8% |
Reaction Steps
100 mg of 10% palladium-carbon was added to 20 ml of an ethanol solution containing 546 mg of 3-nitro-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one, followed by stirring overnight in hydrogen atmosphere. The reaction mixture was filtered through silica gel and concentrated, to give 411 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07563811B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-8097c69d60324cfea34958ef5b74cc03 |
| Source note | uspto-grants-2009_07 |