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Potassium Carbonate → Ethyl 4-[4-(2-nitro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-[2-Nitro-4-(trifluoromethyl)phenoxy]phenol | HCID 23325101 | — |
| 反応物 | Ethyl 4-bromo-3-methoxypent-2-enoate | HCID 53787831 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Ethyl 4-[4-(2-nitro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoate | HCID 53972465 | — |
反応手順
A mixture of 4-(2-nitro-4-trifluoromethylphenoxy)phenol (9.36 mm)., ethyl 4-bromo-3-methoxy-2-pentenoate (12 mm.) and K2CO3 (14 mm.) in acetone (20 ml.) is refluxed for 24 hours. After filtration, the filtrate is concentrated and the oily residue chromatographed on silica gel to yield ethyl 4-[4-(2-nitro-4-trifluoromethylphenoxy)phenoxy]-3-methoxy-2-pentenoate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04429167 |
| 出典データセット | uspto-grants-1984_01 |
| ORD ID | ord-f93849dfae0149c1a32605eec6e577a6 |
| 出典メモ | uspto-grants-1984_01 |