HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrabutylammonium borohydride → HCID 70508934, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrabutylammonium borohydride | HCID 169536 | — |
| Reactant | HCID 70507356 | HCID 70507356 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 70508934 | HCID 70508934 | — |
Reaction Steps
By the procedures of Examples 3 and 6, pivaloyloxymethyl 2-methyl-1-oxo-6-(2-phenoxyacetamido)carbapenam-3-carboxylate (102 mg., 0.23 mmole) in 3 ml. of methylene chloride was reduced by the action of tetrabutylammonium borohydride (15 mg., 0.06 mmole) and isolated to yield purified pivaloyloxymethyl 1-hydroxy-2-methyl-6-(2-phenoxyacetamido)carbapenam-3-carboxylate [68 mg.; Rf 0.26 (4:1 chloroform:ethyl acetate; ir (CH2Cl2) 1775, 1750, 1675 cm-1 ].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04429128 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-75f9b4c77b894eb9b10b2dcd9c830864 |
| Source note | uspto-grants-1984_01 |