1,1'-Carbonyldiimidazole → HCID 9793874, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 2 g (16 mmol) of 2-hydroximinohomopiperidine (Maybridge) in 20 mL of methylene chloride (CH2Cl2) was added 2.5 g (16 mmol) of 1,1′-carbonyldiimidazole (CDI). This was stirred at 25° C. for six days. This solution was diluted with CH2Cl2, washed with water, dried (MgSO4), filtered and concentrated to afford 2.2 g (89% yield) of the title compound as a white semi-solid. Mass Spectra for C7H10N2O2: M+H155. 1H NMR,(CDCl3) d 1.5-1.9 (m, 6H), 2.6 (dd, 2H), 3.6 (dd, 2H). 13C NMR (CDCl3) d 25.3, 26.0, 28.2, 30.2, 43.7, 159.1, 161.6.

Provenance & Evidence