HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21786872, compound → HCID 22596712, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21786872 | HCID 21786872 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22596712 | HCID 22596712 | 96% |
Reaction Steps
A suspension of the above amine (450 mg, 2.0 mmol) in DMF (15 mL) was hydrogenated over 10% Pd/C (60 mg) at 50 psi for 20 h. The catalyst was removed by filtration and the solvent removed to give 5,6-diaminoquinazolin-2,4-dione (369 mg, 95%) as a dark solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489328B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-fda0d4c99d084219840ceec4bad7ee86 |
| Source note | uspto-grants-2002_12 |