1-Bromo-2-Chloroethane → HCID 10132662, compound

HRID 2296733Notes

Reaction equation

HRID 2296733 reaction equation
[CH:1]([NH:4][CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2].Cl[CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[N:19]=[C:20]3[C:25]([CH3:26])=[CH:24][CH:23]=[CH:22][N:21]3[CH:27]=2)=[CH:14][CH:13]=1.BrCCCl>>[CH:1]([N:4]([CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2[N:19]=[C:20]3[C:25]([CH3:26])=[CH:24][CH:23]=[CH:22][N:21]3[CH:27]=2)=[CH:14][CH:13]=1)[CH:5]([CH3:7])[CH3:6])([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 78491-Bromo-2-ChloroethaneHCID 7912DiisopropylamineHCID 70159838HCID 70159838, compound

Product 1

HCID 10132662HCID 10132662, compound

Procedure

The title compound was prepared by condensing di-iso-propylamine with 2-(4-chloroethoxyphenyl)-8-methylimidazo[1,2-a]pyridine. 2-(4-Chloroethoxyphenyl)-8-methylimidazo[1,2-1]pyridine was prepared according the procedure described in Example 1 above using 1-bromo-2-chloroethane in place of 1-bromo-3-chloropropane. Analysis Calc'd for C22H29N3O 3HCl; C, 7.16; H, 55.18; N, 8.77. Found: C, 7.13; H, 55.56; N, 8.8.

Sources & evidence

ORD record
ord-119055f0361e4f18800b6be15f832fe1
Source dataset
uspto-grants-2002_12
Patent number
US06489337B1

Reaction notes

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