Dibutylamine → HCID 10110274, compound

HRID 2296736Notes

Reaction equation

HRID 2296736 reaction equation
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][C:7]=1[CH3:22].[CH2:23]([NH:27][CH2:28][CH2:29][CH2:30]C)[CH2:24][CH2:25]C>>[CH2:23]([N:27]([CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]3[C:19]([CH3:20])=[CH:18][CH:17]=[CH:16][N:15]3[CH:21]=2)=[CH:8][C:7]=1[CH3:22])[CH2:28][CH2:29][CH3:30])[CH2:24][CH3:25]

Participants

3

Reactant 2

HCID 8148DibutylamineHCID 14201489HCID 14201489, compound

Product 1

HCID 10110274HCID 10110274, compound

Procedure

The product of Step C (3.0 g) and dibutylamine (10.0 mL) were heated at reflux temperature for 18 hours. The reaction was evaporated and the residue was purified via silica gel chromatography (dichloromethane/methanol) to give the title compound.

Workup

  1. temperatureat reflux temperature for 18 hours
  2. customThe reaction was evaporated
  3. customthe residue was purified via silica gel chromatography (dichloromethane/methanol)

Sources & evidence

ORD record
ord-1495f26494be4ab99696ff85419c3f2d
Source dataset
uspto-grants-2002_12
Patent number
US06489337B1

Reaction notes

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