HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(2-Acetoxyethyl)-N-methylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(N-Methylanilino)ethanol | HCID 62340 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2-Acetoxyethyl)-N-methylaniline | HCID 12570555 | — |
Reaction Steps
A 1 L flask was charged with 2-(N-methylanilino)ethanol (8) (151.3 g, 1 mole), methylene chloride (250 mL), and triethylamine (151 g, 1.48 mole). Acetic anhydride (153.35 g, 1.5 mole) was added to the solution at room temperature through an addition funnel. The product (7) was collected by vacuum distillation (122 g, bp 110° C. at 400 micron Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489399B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-8142dca0c87c48fd83449742c3c319fd |
| Source note | uspto-grants-2002_12 |