HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 22318959, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | HCID 22318940 | HCID 22318940 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | HCID 22318959 | HCID 22318959 | 62.3% |
Reaction Steps
52 mg of 1-[3-(benzyloxy)phenyl]-3-(2-cyanophenyl)-5-(2-pyridyl)-1,2-dihydropyridin-2-one and 20 mg of 5% palladium-carbon were added to 3 ml of methanol, followed by stirring at room temperature in hydrogen atmosphere overnight. After the resulting insoluble matters were filtered off, the filtrate was evaporated. The residue was purified by silica gel chromatography (ethyl acetate/hexane system), to give 26 mg the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07563811B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-cb12a98aa78446bfba5a5fbeaae6a987 |
| Source note | uspto-grants-2009_07 |