HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 5-Methyl-4-tert-butyldimethylsilyloxymethyl-2-oxo-1,3-dioxolene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilane | HCID 5072427 | — |
| Reactant | 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one | HCID 10510878 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-Methyl-4-tert-butyldimethylsilyloxymethyl-2-oxo-1,3-dioxolene | HCID 23511477 | — |
Reaction Steps
A solution of 5-methyl-4-hydroxymethyl-2-oxo-1,3-dioxolene (1 mmole) in DMF was treated with tert-butyldimethylsilane (1.2 mmole) and imidazole (2.2 mmole) at 25° C. for 24 h. Extraction and chromatography gave 5-methyl-4-tert-butyldimethylsilyloxymethyl-2-oxo-1,3-dioxolene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489476B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-ccf624c64f9d411097bc5bb092f48c0a |
| Source note | uspto-grants-2002_12 |