HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylstannane → HCID 22280667, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | HCID 53657582 | HCID 53657582 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 22280667 | HCID 22280667 | — |
Reaction Steps
A solution of diethyl 4-(tert-butyldiphenylsilyloxy)-3-phenoxythiocarbonyloxy-2,2-difluorobutylphosphonate (1 mmole) in toluene (1 mL) was treated with tri-n-butyltin hydride (1.5 mmole) and AIBN (0.1 mmole), and the resulting reaction mixture was heated to reflux for 2 h. Evaporation and chromatography gave diethyl 4-(tert-butyldiphenylsilyloxy)-2,2-difluorobutylphosphonate as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489476B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-e846690f254b46cabe59f7ef26251678 |
| Source note | uspto-grants-2002_12 |