Sodium Carbonate → Beta-citronellol, (S)-

Participants

Reaction Steps

Into a 100-ml autoclave were introduced 20.5 g (132.8 mmol) of (R)-citronellal, 1.0 g (5%, wt/wt) of a copper-chromium catalyst, and 0.04 g (0.2%, wt/wt) of sodium carbonate. After the atmosphere in the system was replaced with hydrogen, the reaction mixture was vigorously agitated in a hydrogen atmosphere (3.4 MPa) at 130° C. for 4.5 hours and then cooled. Thereafter, the catalyst was removed by filtration. The crude citronellol obtained was distilled under reduced pressure (70° C./1,870 Pa) to obtain 15.15 g of (S)-citronellol. Yield, 73%. Purity, 98.6% (of which α-citronellol accounted for 3.4%).

Provenance & Evidence