HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phthalimide → 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phthalimide | HCID 6809 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2,2',4'-Trichloroacetophenone | HCID 20250 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione | HCID 736778 | — |
Reaction Steps
1 mmol of 2,4-dichlorophenacyl chloride in DMF was added drop wise to 2 mmol of phthalimide and 2 mmol of Cs2CO3 in DMF at room temperature for fourteen hours and then purified by trituration with diethyl ether to obtain 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]isoindoline-1,3-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489344B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-34e35367a85c40f0a04ba9730927e56c |
| Source note | uspto-grants-2002_12 |