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HRID229723

反应详情

EQUATION

反应方程式

HRID 229723 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)[C@H](C)NC(=O)OC(C)(C)C)C1
HCID68844509

未命名化合物

PRODUCTS

生成物

1
结构：CC1Cc2nnc(-c3cccc(C(F)(F)F)c3)cc2C(OC(=O)[C@H](C)N)C1.Cl.Cl
HCID68845508

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

2 次

PROCEDURE

实验过程

5-(N-(tert-butoxycarbonyl)-L-alanyl)oxy-7-methyl-3-(3-trifluoromethylphenyl)-5,6,7,8-tetrahydrocinnoline obtained in Example 31 was dissolved in dioxane (0.5 mL, followed by adding a 4N HCl solution/dioxane (0.5 mL) under ice cooling and reacting over night. The reaction liquid was concentrated to dryness to obtain an objective compound as white solid.

WORKUP

后处理

  1. waitreacting over night
  2. customThe reaction liquid
  3. concentrationwas concentrated to dryness