1,2-Dimethylimidazole → [4-(2,4-Dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl](2-{[5-(trifluoro-methyl)(2-pyridyl)]amino}ethyl)amine

Participants

Role	Name	HCID	Charge
Reactant	1,2-Dimethylimidazole	HCID 15617	—
Reactant	2-Chloro-5-(trifluoromethyl)pyridine	HCID 92342	—
Reactant	Chir-98023	HCID 9847557	—
Product	[4-(2,4-Dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl](2-{[5-(trifluoro-methyl)(2-pyridyl)]amino}ethyl)amine	HCID 22142893	—

Reaction Steps

[4-(2,4-dichlorophenyl)-5-(1-methylimidazol-2-yl)pyrimidin-2-yl](2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine was prepared from 1,2-dimethylimidazole and 2-chloro-5-(trifluoromethyl)pyridine using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06489344B1
Source dataset	uspto-grants-2002_12
ORD ID	ord-0634df89b31e417eb86658f9daedb844
Source note	uspto-grants-2002_12