Chir-98023 → HCID 22142590, compound

HRID 2297259Notes

Reaction equation

HRID 2297259 reaction equation
[Br:1]C1C=C(C2C(C(Cl)=O)=CC=CC=2)[ClH]C=1.[Cl:16][C:17]1[CH:22]=[C:21](Cl)[CH:20]=[CH:19][C:18]=1[C:24]1[C:29]([C:30]2[NH:31][CH:32]=[CH:33][N:34]=2)=[CH:28][N:27]=[C:26]([NH:35][CH2:36][CH2:37][NH:38][C:39]2[CH:44]=[CH:43][C:42]([N+:45]([O-:47])=[O:46])=[CH:41][N:40]=2)[N:25]=1>>[Br:1][C:21]1[CH:20]=[CH:19][C:18]([C:24]2[C:29]([C:30]3[NH:31][CH:32]=[CH:33][N:34]=3)=[CH:28][N:27]=[C:26]([NH:35][CH2:36][CH2:37][NH:38][C:39]3[CH:44]=[CH:43][C:42]([N+:45]([O-:47])=[O:46])=[CH:41][N:40]=3)[N:25]=2)=[C:17]([Cl:16])[CH:22]=1

Participants

2

Reactant 1

HCID 9847557Chir-98023

Product 1

HCID 22142590HCID 22142590, compound

Procedure

[4-(4-bromo-2-chlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine was prepared from 4-bromo-2-chlorolbenzoyl chloride using the general method for [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Sources & evidence

ORD record
ord-03aed3d4ebf44f0d9aebad6e68aba5e6
Source dataset
uspto-grants-2002_12
Patent number
US06489344B1

Reaction notes

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