HCID 178430853, compound → HCID 178430852, compound

HRID 2297262Notes

Reaction equation

HRID 2297262 reaction equation
[Br:1]C1C=C(C2C(C(Cl)=O)=CC=CC=2)[ClH]C=1.[Cl:16][C:17]1[CH:22]=[C:21](Cl)[CH:20]=[CH:19][C:18]=1[C:24]1[C:29]([C:30]2[NH:31][CH:32]=[C:33]([CH3:35])[N:34]=2)=[CH:28][N:27]=[C:26]([NH:36][CH2:37][CH2:38][NH:39][C:40]2[N:45]=[CH:44][C:43]([C:46]#[N:47])=[CH:42][CH:41]=2)[N:25]=1>>[Br:1][C:21]1[CH:20]=[CH:19][C:18]([C:24]2[C:29]([C:30]3[NH:31][CH:32]=[C:33]([CH3:35])[N:34]=3)=[CH:28][N:27]=[C:26]([NH:36][CH2:37][CH2:38][NH:39][C:40]3[N:45]=[CH:44][C:43]([C:46]#[N:47])=[CH:42][CH:41]=3)[N:25]=2)=[C:17]([Cl:16])[CH:22]=1

Participants

2

Reactant 1

HCID 178430853HCID 178430853, compound

Product 1

HCID 178430852HCID 178430852, compound

Procedure

6-[(2-{[4-(4-bromo-2-chlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile was prepared from 4-bromo-2-chlorolbenzoyl chloride using the general method for 6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino)ethyl)amino]pyridine-3-carbonitrile.

Sources & evidence

ORD record
ord-c7b968af94ae4342b7e89e9d593ee220
Source dataset
uspto-grants-2002_12
Patent number
US06489344B1

Reaction notes

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