2-(Benzimidazolyl)-1-(2,4-dichlorophenyl)ethanone → 2-Benzimidazolyl-1-(2,4-dichlorophenyl)-3(dimethylamino)prop-2-en-1-one

HRID 2297283Notes

Reaction equation

HRID 2297283 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:20])[C:10]([C:15]1C=CN[N:16]=1)=[CH:11][N:12]([CH3:14])[CH3:13].[N:21]1[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=2NC=1CC(C1C=CC(Cl)=CC=1Cl)=O>>[N:21]1[C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=2[NH:16][C:15]=1[C:10](=[CH:11][N:12]([CH3:13])[CH3:14])[C:9]([C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])=[O:20]

Participants

3

Reactant 2

HCID 221424812-(Benzimidazolyl)-1-(2,4-dichlorophenyl)ethanoneHCID 178483574HCID 178483574, compound

Product 1

HCID 538346012-Benzimidazolyl-1-(2,4-dichlorophenyl)-3(dimethylamino)prop-2-en-1-one

Procedure

Made using the same procedure as for 1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-pyrazolylprop-2-en-1-one except that 2-benzimidazolyl-1-(2,4-dichlorophenyl)ethan-1-one (V, 1.0 g, 3.3 mmol) was used. The crude residue was used without purification.

Workup

  1. customThe crude residue was used without purification

Sources & evidence

ORD record
ord-5ad1cd9d396f4332b678e877726f28f7
Source dataset
uspto-grants-2002_12
Patent number
US06489344B1

Reaction notes

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