HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione → 2-{2-(2,4-Dichlorophenyl)-1-[(dimethylamino)methylene]-2-oxoethyl}isoindoline 1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione | HCID 736778 | — |
| Solvent | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | 2-{2-(2,4-Dichlorophenyl)-1-[(dimethylamino)methylene]-2-oxoethyl}isoindoline 1,3-dione | HCID 54018371 | — |
Reaction Steps
1 mmol of 2-[2-(2,4-dichlorophenyl)-2-oxoethyl]isoindoline-1,3-dion was heated to 80° C. in neat N,N-dimethylformamidedimethyl acetal for six hours. The reaction mixture was concentrated in vacuo and purified by trituration with diethyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489344B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-aaff91e21c0841bbb8757f9bb79ba7f2 |
| Source note | uspto-grants-2002_12 |