HCID 54276904, compound → HCID 54286881, compound

Participants

Reaction Steps

To a stirred solution of 3-(4′-heptyloxybiphenyl-4-yl)acrylic acid ethyl ester (2.65 g, 7.23 mmol) in CH2Cl2 (60 ml) was added palladium on activated carbon (Pd ca.10 wt %, 1.07 g), and then the mixture was set under H2 atmosphere. After being stirred for 2 h, the mixture was filtered through a pad of Celite and washed with CH2Cl2. Filtrate and washings were combined and concentrated in vacuo to give 3-(4′-heptyloxybiphenyl-4-yl)propionic acid ethyl ester (crude, 2.74 g) which was used for the next step without further purification.

Provenance & Evidence