Sodium Hydroxide → HCID 18381720, compound

Participants

Reaction Steps

A solution comprised of ethyl 2-benzoylamino-4-phenylsulfanylbutyrate (340 mg, 1.0 mmol) in methanol (4 mL) was treated with 1 N aqueous sodium hydroxide (2 mL) and stirred at ambient temperature for 3 hours. The reaction mixture was cooled on ice, acidified to pH 1 and then extracted with ethyl acetate. The extract was concentrated to provide 2-benzoylamino-4-phenylsulfanylbutyric acid (304 mg, 1.0 mmol).

Provenance & Evidence