反应详情

5 g of benzyl 4-(methoxycarbonylmethyloxy)benzoate were dissolved in methanol/ethyl acetate and hydrogenated in the presence of 600 mg of catalyst (Pd/C, 10% strength). After flushing with inert gas, the catalyst was filtered off and the filtrate was concentrated in vacuo. The residue was triturated with diisopropyl ether/heptane (9/1) and filtered off with suction. Yield: 3.3 g.

1. customAfter flushing with inert gas
2. filtrationthe catalyst was filtered off
3. concentrationthe filtrate was concentrated in vacuo
4. customThe residue was triturated with diisopropyl ether/heptane (9/1)
5. filtrationfiltered off with suction