Ethanol → HCID 131723676, compound

Participants

Reaction Steps

0.14 ml (1.15 eq.) of thionyl chloride were added at −10° C. to 5 ml of ethanol and stirred for 10 min at this temperature. Then 1 g (1.66 mmol) of the compound of Example 1 were added as a suspension in 10 ml of ethanol. Under stirring, the mixture was warmed to room temperature and stirred for further 5 hours. The solution which had meanwhile become clear, was evaporated in vacuo, the residue was dissolved in water and, after filtration, subjected to lyophilization. Yield: 0.85 g of a colourless, amorphous solid. MS (ES+): m/e=511 (M+H+, 100%).

Provenance & Evidence