참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | (2E)-3-(3-Thienyl)-2-propenoic acid | HCID 735793 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Ethyl (2E)-3-(3-thienyl)-2-propenoate | HCID 10986919 | — |
반응 단계
11.5 g of potassium carbonate and 6.8 ml of iodoethane are added to 11 g of (E)-3-(3-thienyl)-2-propenoic acid, obtained in step 4.1, in solution in 50 ml of dimethylformamide, and the mixture is stirred for 48 hours at 20° C. The medium is taken up in ethyl acetate and it is washed with water. The organic phase is dried over anhydrous sodium sulphate and it is concentrated to give 12.5 g of oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07563903B2 |
|---|
| 출처 데이터셋 | uspto-grants-2009_07 |
|---|
| ORD ID | ord-f188bc0048d84992b5b5bedb61a293b0 |
|---|
| 출처 메모 | uspto-grants-2009_07 |
|---|
