HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 707441, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-[(2-Acetylphenyl)amino]-5-oxopentanoic acid | HCID 18381917 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | HCID 707441 | HCID 707441 | 50% |
Reaction Steps
4-(N-(2-acetylphenyl)carbamoyl)butanoic acid (4.87 g) was dissolved in 2% aqueous potassium hydroxide solution (100 ml), and the resulting solution was heated to reflux overnight. Concentrated hydrochloric acid was added to the reaction solution and the precipitated solids were recrystallized from methanol/chloroform/ethyl acetate to obtain 2.26 g of 3-(4-methyl-2-oxo-3-hydroquinolyl)propanoic acid as colorless crystals. Yield: 50%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492364B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-a370dbfa530a4a6c9d5ca37245fac52f |
| Source note | uspto-grants-2002_12 |