2-(Tributylstannyl)pyridine → HCID 10203901, compound

Participants

Reaction Steps

The product from step A above, (0.4 g, 0.896 mmol), 2-tributylstannanylpyridine (0.8 g, 2.17 mmol) and Pd(PPh3)4 (0.12 g, 0.104 mmol) were stirred in 1,4-dioxane (5 mL) at 88° C. for 24 h. The reaction mixture was filtered through a plug of Celite with CH2Cl2 and then concentrated to a small volume. Preparative TLC (3:7 ethyl acetate/hexane; then 5% CH3OH/CH2Cl2) yielded the product as a yellow solid.

Provenance & Evidence