4-N-Propylbenzenesulphonyl chloride → Acetate

HRID 2297544Notes

Reaction equation

HRID 2297544 reaction equation
CC1O[N:5]=[C:4]([C:7]2[CH:8]=[C:9]([C:13]([N:15]3[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]3)=[O:14])[CH:10]=[CH:11][CH:12]=2)[N:3]=1.[CH2:21]([C:24]1[CH:29]=[CH:28][C:27]([S:30](Cl)(=[O:32])=[O:31])=[CH:26][CH:25]=1)[CH2:22][CH3:23]>>[CH2:21]([C:24]1[CH:29]=[CH:28][C:27]([S:30]([N:18]2[CH2:17][CH2:16][N:15]([C:13]([C:9]3[CH:8]=[C:7]([CH:12]=[CH:11][CH:10]=3)[C:4]([NH2:3])=[NH:5])=[O:14])[CH2:20][CH2:19]2)(=[O:32])=[O:31])=[CH:26][CH:25]=1)[CH2:22][CH3:23].[C:13]([O-:14])(=[O:31])[CH3:9]

Participants

4

Reactant 2

HCID 27372224-N-Propylbenzenesulphonyl chlorideHCID 69979907HCID 69979907, compound

Product 2

HCID 175AcetateHCID 15860384HCID 15860384, compound

Procedure

Similarly, reaction of [3-(5-methyl-[1,2,4]oxadiazol-3-yl)phenyl]piperazin-1-ylmethanone with 4-propyl-phenylsulphonyl chloride and subsequent hydrogenation gives the compound 3-[4-(4-propylphenylsulphonyl)piperazine-1-carbonyl]benzamidine, acetate, FAB 415.

Sources & evidence

ORD record
ord-6f957ceafaaa4620b6bdcc536988d158
Source dataset
uspto-grants-2002_12
Patent number
US06492368B1

Reaction notes

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