Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Product | 2-Isopropoxypyrimidine | HCID 22138853 | — |
Reaction Steps
A 2-chloropyrimidine was dissolved in isopropyl alcohol to which was added diisopropylamine. The reaction was heated in a sealed tube for ten days at 130° C. The cooled reaction mixture was concentrated, and the product purified via silica gel column chromatography to yield the 2-isopropoxypyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06492372B1 |
|---|
| Source dataset | uspto-grants-2002_12 |
|---|
| ORD ID | ord-3b3454c653f243d69fd031d8edb90276 |
|---|
| Source note | uspto-grants-2002_12 |
|---|
