Cornforth reagent → HCID 18382510, compound

Participants

Reaction Steps

0.3 g of 6-benzyl-7-cyclopentyl-4-ethyl-2-hydroxymethyl-imidazo[4,5-e]-s-triazolo[1,5-a]pyrimidin-5-one (for preparation see Synthesis Example I) are dissolved in 1.1 ml of dichloromethane and 0.45 g of pyridinium dichromate are added. The brown suspension obtained is stirred for about 24 hours at ambient temperature. The solvent is distilled off and the residue remaining is stirred with an ethyl acetate/cyclohexane mixture (2:1.5 ml). The clear, light yellow supernatant solution is filtered through silica gel. After the solvent has been distilled off, 0.15 g of the title compound are left in the form of a colourless resin.

Provenance & Evidence