HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 4-Methoxy-3-(trifluoromethyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Methoxy-3-(trifluoromethyl)benzoic acid | HCID 2775295 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Methoxy-3-(trifluoromethyl)benzoyl chloride | HCID 2775298 | — |
Reaction Steps
The title compound was prepared from 4-methoxy-3-trifluoromethylbenzoic acid with oxalyl chloride and DMF in chloroform at room temperature [D. Levin, Chem. Br., 1977, 201] followed by evaporation in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492378B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-28af2a9d92a34fe3ab6e4b28adf33835 |
| Source note | uspto-grants-2002_12 |