HCID 18383170, compound → HCID 18383132, compound

Participants

Reaction Steps

By reaction of 2-isopropyl-3,5-dihydro-7-bromoimidazo-[4,5-c]pyridin-4-one with CuCN in DMF by customary methods (Ellefson et al., J. Med. Chem. 1976, 19), 2-isopropyl-3,5-dihydro-7-cyanoimidazo[4,5-c]pyridin-4-one is obtained. This is then hydrolysed and alkylated analogously to Examples 1 and 4 and hydrogenated analogously to Example 3. In this process, the carboxylic acid derivatives listed under Example 6 are obtained.

Provenance & Evidence