2-Furancarboxylic acid, hydrazide → 3-(2-furyl)-4(4-methoxybenzyl)-5-{[4-(trifluoromethyl)benzyl]thio}-4H-1,2,4-triazole

HRID 229769Notes

Reaction equation

HRID 229769 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([NH:8][NH2:9])=O.[CH3:10][O:11][C:12]1[CH:21]=[CH:20][C:15]([CH2:16][N:17]=[C:18]=[S:19])=[CH:14][CH:13]=1.[F:22][C:23]([F:33])([F:32])[C:24]1[CH:31]=[CH:30][C:27]([CH2:28]Br)=[CH:26][CH:25]=1>>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[N:17]([CH2:16][C:15]2[CH:20]=[CH:21][C:12]([O:11][CH3:10])=[CH:13][CH:14]=2)[C:18]([S:19][CH2:28][C:27]2[CH:26]=[CH:25][C:24]([C:23]([F:22])([F:32])[F:33])=[CH:31][CH:30]=2)=[N:9][N:8]=1

Participants

4

Reactant 3

HCID 187312-Furancarboxylic acid, hydrazideHCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 1231974-Methoxybenzyl isothiocyanate

Product 1

HCID 112016463-(2-furyl)-4(4-methoxybenzyl)-5-{[4-(trifluoromethyl)benzyl]thio}-4H-1,2,4-triazole

Procedure

This compound was synthesized using the same methodology as described in Example 1 above, using 2-furancarboxylic acid hydrazide, 4-methoxybenzyl isothiocyanate and 4-trifluoromethylbenzyl bromide as the starting materials. (M+H)+−446.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-2528c542ede94208bf1350645a929deb
Source dataset
uspto-grants-2009_07
Patent number
US07563905B2

Reaction notes

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