HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenylboronic acid → [6-(4-Fluoro-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-(1H-indol-5-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | (6-Bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine | HCID 18383051 | — |
| Product | [6-(4-Fluoro-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-(1H-indol-5-yl)-amine | HCID 9906899 | — |
Reaction Steps
The title compound was prepared from p-fluorobenzeneboronic acid and (6-bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine by a procedure analogous to example 2. 1H NMR (400 MHz, DMSO) d 11.4 (s, 1H), 8.82 (s, 1H), 7.79 (m, 4H), 7.41 (m, 5H), 7.21 (d, 1H). 6.50 (s, 1H), M.P. 193-205° C.; LC-MS: 361 (MH+); HPLC RT: 4.88 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492383B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-1b377b5149d846659d7c26b186bac2ab |
| Source note | uspto-grants-2002_12 |