HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Methoxyphenyl)boronic acid → (1H-Indol-5-yl)-[6-(4-methoxy-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Reactant | (6-Bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine | HCID 18383051 | — |
| Product | (1H-Indol-5-yl)-[6-(4-methoxy-phenyl)-thieno[3,2-d]pyrimidin-4-yl]-amine | HCID 18383077 | — |
Reaction Steps
The title compound was prepared from p-methoxybenzeneboronic acid and (6-bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine by a procedure analogous to example 2. 1H NMR (400 MHz, DMSO) d 11.4 (s, 1H),11.2 (s, 1H), 8.81 (s, 1H), 7.55 (m, 6H), 7.20 (d, 1H). 7.05 (m, 2H), 6.50 (s, 1H), 3.79 (s, 3H). M.P. 150-180° C.; LC-MS: 373 (MH+); HPLC RT: 4.45 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492383B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-e8b6f48a0ca542699c4116e8db9582da |
| Source note | uspto-grants-2002_12 |