HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Formylphenylboronic Acid → 4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Formylphenylboronic Acid | HCID 591073 | — |
| Reactant | (6-Bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine | HCID 18383051 | — |
| Product | 4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde | HCID 18382759 | — |
Reaction Steps
The title compound was prepared from p-formylbenzeneboronic acid and (6-bromo-thieno[3,2-d]pyrimidin-4-yl)-(1H-indol-5-yl)-amine by a procedure analogous to example 2. 1H NMR (400 MHz, DMSO) d 11.2 (s, 1H), 9.95 (s, 1H), 8.85 (s, 1H), 7.90 (m, 6H), 7.75 (s, 1H), 7.46 (m, 3H), 7.20 (d, 1H), 6.49 (s, 1H), 2.28 (s, 3H), LC-MS: 371 (MH+); HPLC RT: 4.10 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492383B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-0b62d3d7e263491189ae4748b2b575c5 |
| Source note | uspto-grants-2002_12 |