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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297772Generated: October 31, 2026

2-Morpholinoethylamine → (1H-Indol-5-yl)-(6-{4-[(2-morpholin-4-yl-ethylamino)-methyl]-phenyl}-thieno[3,2-d]pyrimidin-4-yl)-amine

https://huagongshe.com/reaction/2297772

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MorpholinoethylamineHCID 408285—
Reactant4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehydeHCID 18382759—
Product(1H-Indol-5-yl)-(6-{4-[(2-morpholin-4-yl-ethylamino)-methyl]-phenyl}-thieno[3,2-d]pyrimidin-4-yl)-amineHCID 18382888—

Reaction Steps

The title compound was prepared from N-(2-aminoethyl)morpholine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 100-111° C.; LC-MS: 485 (MH+); HPLC RT: 4.23 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492383B1
Source datasetuspto-grants-2002_12
ORD IDord-5c2db87673a3444f925d9b4cbf577836
Source noteuspto-grants-2002_12