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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297774Generated: October 31, 2026

1-Methylpiperazine → (1H-Indol-5-yl)-{6-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-thieno[3,2-d]pyrimidin-4-yl}-amine

https://huagongshe.com/reaction/2297774

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant4-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehydeHCID 18382759—
Product(1H-Indol-5-yl)-{6-[4-(4-methyl-piperazin-1-ylmethyl)-phenyl]-thieno[3,2-d]pyrimidin-4-yl}-amineHCID 18382974—

Reaction Steps

The title compound was prepared from N-methylpiperazine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by the procedure analogous to example 17.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06492383B1
Source datasetuspto-grants-2002_12
ORD IDord-36906325f53143ee935db9d1e787d74c
Source noteuspto-grants-2002_12