1-(3-Aminopropyl)-2-pyrrolidinone → HCID 18382965, compound

HRID 2297782Notes

Reaction equation

HRID 2297782 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:9][CH2:8][CH2:7][C:6]1=[O:10].[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21]3[C:22]4[S:29][C:28]([C:30]5[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=5)=[CH:27][C:23]=4[N:24]=[CH:25][N:26]=3)=[CH:17][CH:18]=2)[CH:13]=[CH:12]1>>[NH:11]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21]3[C:22]4[S:29][C:28]([C:30]5[CH:37]=[CH:36][C:33]([CH2:34][NH:1][CH2:2][CH2:3][CH2:4][N:5]6[CH2:9][CH2:8][CH2:7][C:6]6=[O:10])=[CH:32][CH:31]=5)=[CH:27][C:23]=4[N:24]=[CH:25][N:26]=3)=[CH:17][CH:18]=2)[CH:13]=[CH:12]1

Participants

3

Reactant 2

HCID 821111-(3-Aminopropyl)-2-pyrrolidinoneHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382965HCID 18382965, compound

Procedure

The title compound was prepared from 1-(3-amino-propyl)-pyrrolidin-2-one and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d)pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 139-146° C.; LC-MS: 497 (MH+); HPLC RT: 4.01 minutes.

Sources & evidence

ORD record
ord-73691fad2d8742bd9b94db5cabcfa9d6
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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