Morpholine → HCID 18382793, compound

HRID 2297783Notes

Reaction equation

HRID 2297783 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH:7]1[C:15]2[C:10](=[CH:11][C:12]([NH:16][C:17]3[C:18]4[S:25][C:24]([C:26]5[CH:33]=[CH:32][C:29]([CH:30]=O)=[CH:28][CH:27]=5)=[CH:23][C:19]=4[N:20]=[CH:21][N:22]=3)=[CH:13][CH:14]=2)[CH:9]=[CH:8]1>>[NH:7]1[C:15]2[C:10](=[CH:11][C:12]([NH:16][C:17]3[C:18]4[S:25][C:24]([C:26]5[CH:33]=[CH:32][C:29]([CH2:30][N:1]6[CH2:6][CH2:5][O:4][CH2:3][CH2:2]6)=[CH:28][CH:27]=5)=[CH:23][C:19]=4[N:20]=[CH:21][N:22]=3)=[CH:13][CH:14]=2)[CH:9]=[CH:8]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 18382793HCID 18382793, compound

Procedure

The title compound was prepared from morpholine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 141-152° C.; LC-MS: 442 (MH+); HPLC RT: 4.10 minutes.

Sources & evidence

ORD record
ord-532fb59e2c834c67823e931f23eeed5d
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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