Cyclopropylamine → HCID 9822910, compound

HRID 2297786Notes

Reaction equation

HRID 2297786 reaction equation
[CH:1]1([NH2:4])[CH2:3][CH2:2]1.[NH:5]1[C:13]2[C:8](=[CH:9][C:10]([NH:14][C:15]3[C:16]4[S:23][C:22]([C:24]5[CH:31]=[CH:30][C:27]([CH:28]=O)=[CH:26][CH:25]=5)=[CH:21][C:17]=4[N:18]=[CH:19][N:20]=3)=[CH:11][CH:12]=2)[CH:7]=[CH:6]1>>[CH:1]1([NH:4][CH2:28][C:27]2[CH:26]=[CH:25][C:24]([C:22]3[S:23][C:16]4[C:15]([NH:14][C:10]5[CH:9]=[C:8]6[C:13](=[CH:12][CH:11]=5)[NH:5][CH:6]=[CH:7]6)=[N:20][CH:19]=[N:18][C:17]=4[CH:21]=3)=[CH:31][CH:30]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 183827594-(4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde

Product 1

HCID 9822910HCID 9822910, compound

Procedure

The title compound was prepared from cyclopropylamine and 4-[4-(1H-indol-5-ylamino)-thieno[3,2-d]pyrimidin-6-yl]-benzaldehyde by a procedure analogous to example 17. M.P. 176-180° C.; LC-MS: 412 (MH+); HPLC RT: 4.10 minutes.

Sources & evidence

ORD record
ord-31140d6fcf69453481c459ccef8be0ee
Source dataset
uspto-grants-2002_12
Patent number
US06492383B1

Reaction notes

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